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Clinical case of Loeffler’s endomyocarditis

https://doi.org/10.18699/SSMJ20230629

Abstract

Eosinophilic endomyocarditis is caused by direct infiltration of heart tissue by eosinophils with the development of specific inflammation. The main etiological factor of the disease is a significant increase in the level of eosinophils in peripheral blood. Loeffler syndrome can be caused by such factors and pathological conditions as idiopathic hypereosinophilic syndrome, allergic diseases, parasitic infections, autoimmune processes, cancer. A clinical case of Loeffler syndrome in an 84-year-old patient with heart, lung, liver, kidney and pancreatic lesions is presented. Difficulties of differential diagnostics of this syndrome because of individual clinical picture and signs of the course are discussed in the article. Timely diagnosis of such a condition will prevent the rapid development of severe complications and carry out appropriate therapy, which will significantly prolong the life of patients with Loeffler syndrome. However, in the presence of nonspecific symptoms, the diagnosis of this disease may be diagnostically difficult for the physician.

About the Authors

S. S. Yashin
Samara State Medical University of Minzdrav of Russia
Russian Federation

Sergey S. Yashin

443099, Samara, Chapaevskaya st., 89



Yu. R. Yunusova
Samara State Medical University of Minzdrav of Russia
Russian Federation

Yulia R. Yunusova - candidate of medical sciences.

443099, Samara, Chapaevskaya st., 89



M. N. Chadayeva
Samara State Medical University of Minzdrav of Russia
Russian Federation

Maria N. Chadaeva

443099, Samara, Chapaevskaya st., 89



References

1. Sheikh H., Siddiqui M., Uddin S.M.M., Haq A., Yaqoob U. The clinicopathological profile of eosinophilic myocarditis. Cureus. 2018;10(12):e3677. doi: 10.7759/cureus.3677

2. Mubarik A., Iqbal A.M. Loeffler endocarditis. Treasure Island (FL): StatPearls Publishing, 2018.

3. Dregoesc M.I., Iancu A.C., Lazar A.A., Balanescu S. Hypereosinophilic syndrome with cardiac involvement in a patient with multiple malignancies. Med. Ultrason. 2018;20(3):399–400. doi: 10.11152/mu-1574

4. Kogan E.A., Blagova O.V., Alieva I.N., Komarov R.N., Kukleva A.D. Clinical and morphological observation of Löffler’s endomyocarditis. Arkhiv patologii = Archive of Pathology. 2020;82(3):47-50. [In Russian]. doi: 10.17116/patol20208203147

5. Muñiz M.T., Eiras M., Selas S., Garcia J. Loeffler endocarditis associated with a massive right intraventricular thrombus. Intensive Care Med. 2018;44(12):2296– 2297. doi: 10.1007/s00134-018-5297-3

6. Alam A., Thampi S., Saba S.G., Jermyn R. Loeffler endocarditis: a unique presentation of right-sided heart failure due to eosinophil-induced endomyocardial fibrosis. Clin. Med. Insights. Case Rep. 2017;10:1179547617723643. doi: 10.1177/1179547617723643

7. Jin X., Ma C., Liu S., Guan Z., Wang Y., Yang J. Cardiac involvements in hypereosinophilia-associated syndrome: Case reports and a little review of the literature. Echocardiography. 2017;34(8):1242–1246. doi: 10.1111/echo.13573

8. Dinis P., Teixeira R., Puga L., Lourenço C., Cachulo M.C., Gonçalves L. Eosinophilic myocarditis: clinical case and literature review. Arq. Bras. Cardiol. 2018;110(6):597–599. doi: 10.5935/abc.20180089

9. Zhong Z., Yang Z., Peng Y., Wang L., Yuan X. Diagnosis and treatment of eosinophilic myocarditis. J. Transl. Autoimmun. 2021;4:100118. doi: 10.1016/j.jtauto.2021.100118

10. Doyen D., Buscot M., Eker A., Dellamonica J. Endomyocardial fibrosis complicating primary hypereosinophilic syndrome. Intensive Care Med. 2018;44(12):2294– 2295. doi: 10.1007/s00134-018-5300-z

11. Bohné M., Bohnen S., Voigt H.C., van der Schalk H., Chung D.U., Willems S., Klingel K., Kivelitz D., Bahlmann E. Systemic thrombo-embolic events in a middle-aged male with Loeffler endocarditis without peripheral eosinophilia-a case report. BMC Cardiovasc. Disord. 2022;22(1):541. doi: 10.1186/s12872022-02911-3

12. Zhao Y., Jiang P., Chen X., Yao G. Case report: Different clinical manifestations of the rare Loeffler endocarditis. Front. Cardiovasc. Med. 2022;9:970446. doi: 10.3389/fcvm.2022.970446


Review

For citations:


Yashin S.S., Yunusova Yu.R., Chadayeva M.N. Clinical case of Loeffler’s endomyocarditis. Сибирский научный медицинский журнал. 2023;43(6):229-234. (In Russ.) https://doi.org/10.18699/SSMJ20230629

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ISSN 2410-2512 (Print)
ISSN 2410-2520 (Online)