Evaluation of deadspace effects created by heat and moisture exchange filter during artificial lung ventilation in newborns
https://doi.org/10.18699/SSMJ20220509
Abstract
Heat and moisture exchange filters create additional dead space, comparable in volume to physiological, in premature newborns. It makes carbon dioxide remove difficultу. Reducing the dead space volume by increasing the flow in the ventilator circuit can lead to the hypocapnia.
Aim of the study was to determine the safety and efficiency of gas flow boost in the ventilator circuit to hypercapnia compensation created by the additional dead space.
Material and methods. The effect of the additional dead space created by a heat and moisture exchange filter on hemoglobin saturation and partial pressure of carbon dioxide at the end of expiration in premature newborns at flows of 5 and 6 l/min was studied.
Results and discussion. It has been demonstrated that flows of 5–6 l/min satisfactorily compensate for the effect of additional deadspace without hypocapnia.
Conclusions. It is possible to recommend the widespread use of heat and moisture exchange filters in newborn weighing at least 1.0 kg during long-term transportation.
About the Authors
A. N. ShmakovRussian Federation
Alexey N. Shmakov, doctor of medical sciences, professor
630087, Novosibirsk, Nemirovich-Danchenko str., 130
630091, Novosibirsk, Krasny ave., 52
K. V. Budarova
Russian Federation
Kristina V. Budarova, candidate of medical sciences
630087, Novosibirsk, Nemirovich-Danchenko str., 130
630091, Novosibirsk, Krasny ave., 52
N. L. Elizar’eva
Russian Federation
Natalya L. Elizar’eva, doctor of medical sciences
630087, Novosibirsk, Nemirovich-Danchenko str., 130
630091, Novosibirsk, Krasny ave., 52
V. N. Kokhno
Russian Federation
Vladimir N. Kokhno, doctor of medical sciences, professor
630087, Novosibirsk, Nemirovich-Danchenko str., 130
References
1. Shmakov A.N., Kokhno V.N. Critical conditions of newborns (technology of remote counseling and evacuation). Saint-Petersburg, Novosibirsk: IPK BIONT, 2007. 168 р. [In Russian].
2. Aleksandrovich Yu.S., Pshenisnov K.V. Respiratory support in critical conditions in pediatrics and neonatology. Guide for doctors. Moscow: GEOTARMedia, 2020. 272 p. [In Russian].
3. Borrows E.L., Lutman D.H., Montgomery M.A., Petros A.J., Ramnarayan P. Effect of patient- and team-related factors on stabilization time during pediatric intensive care transport. Pediatr. Crit. Care Med. 2010;11(4):451–456. doi: 10.1097/PCC.0b013e3181e30ce7
4. Gayton A.K., Kholl G.E. Pulmonary ventilation. In: Textbook of Medical Physiology. Moscow: Logosfera, 2008; 532–533. [In Russian].
5. Hedenstierna G. Respiratory physiology. In: Miller’s Anesthesia, 7th ed. Philadelphia: Churchill Livingstone Elsevier, 2010. P. 361–392. [In Russian].
6. Broughton S.J., Sylvester K.P., Page C.M., Rafferty G.F., Milner A.D., Greenough A. Problems in the measurement of functional residual capacity. Physiol. Meas. 2006;27:99–107. doi: 10.1088/0967-3334/27/2/001
7. Hogg K., Dawson D., Tabor T., Tabor B., Mackway-Jones K. Respiratory dead space measurement in the investigation of pulmonary embolism in outpatients with pleuritic chest pain. Chest. 2005;128(4):2195–2205. doi: 10.1378/chest.128.4.2195
8. Marino P.L. Acute respiratory failure. In: Intensive care. Moscow: GEOTAR-Media, 2010. P. 277–301. [In Russian].
9. Zabolotskikh I.B. Intensive care for respiratory failure. In: Intensive care: national guidance. Vol.1 Ed. I.B. Zabolotskikh, D.N. Protsenko. Moscow: GEOTAR-Media, 2021. P. 449–473. [In Russian].
10. Maier R.F., Obladen M. Respiratory support. In: Intensive care of newborns. Evidence and experience. Moscow: MEDpress-inform, 2021. Р. 171–179. [In Russian].