Role of endothelin-1 and intercellular adhesion molecules in women with miscarriage and infertility
https://doi.org/10.18699/SSMJ20250510
Abstract
A literature review was prepared using information databases eLIBRARY.RU, Google Scholar and PubMed for the period 1990–2025. The selection criterion was information on concentrations of endothelin-1, intercellular adhesion molecules in practically healthy women and patients with nonpregnancy and infertility. Data on the role of endothelin-1 and intercellular adhesion molecules in the mechanisms of regulation of endothelial dysfunction are presented. The necessity of development of normative limits of these molecules’ concentration in women during planning and course of pregnancy as well as identification of therapeutic targets for infertility treatment and prevention of reproductive losses is shown.
Supporting agencies: The work was carried out within the framework of the program of fundamental scientific research of N. Laverov Federal Center for Integrated Arctic Research of UrB RAS “Regulation of the state of immunological reactivity of women of reproductive age living in the northern and arctic territories” (state registration number: 125021902583-8).
About the Author
A. V. Samodova
N. Laverov Federal Center for Integrated Arctic Research of UrB RAS
Russian Federation
Russian Federation
Anna V. Samodova, candidate of biological sciences
163020, Arkhangelsk, Nikolskiy ave., 20
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