Clinical case of Gorham – Stoat syndrome
https://doi.org/10.18699/SSMJ20250120
Abstract
Disappearing bone disease, or Gorham – Stoat syndrome, is a disease of massive osteolysis associated with the proliferation of hemangiotic tissue leading to bone resorption.
Material and methods. The article presents a rare clinical case of Gorham – Stoat syndrome in a 19-year-old patient. The disease manifested at the age of 16 with a lesion of the thoracic vertebrae.
Results. Against the background of the appearance of neurological disorders due to compression of the spinal cord and the development of myelopathy, the patient initially required surgical treatment on the spine. The diagnosis of massive osteolysis is based on anamnesis, X-ray data and histological conclusion. Subsequently, multiple lesions of the ribs, pelvic bones and skull were added. Quite rare in this case is a multi-focal lesion of the skull bones with compression of brain structures.
Conclusions. In differential diagnosis against the background of multifocal resorption of skeletal and cranial bones, it is important to remember about etiological causes that are rarer than hematological and metastatic lesions, including idiopathic osteolysis.
About the Authors
P. G. Shnyakin
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of Minzdrav of Russia; Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Pavel G. Shnyakin, doctor of medical sciences, professor
660022; Partizana Zheleznyaka st., 1; Partizana Zheleznyaka st., 3а; Krasnoyarsk
V. A. Khorzhevsky
Krasnoyarsk Regional Pathological Anatomy Bureau
Russian Federation
Russian Federation
Vladimir A. Khorzhevsky, candidate of medical sciences
660022; Partizanа Zheleznyakа st., 3d; Krasnoyarsk
I. I. Krasnitsky
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Igor I. Krasnitsky
660022; Partizana Zheleznyaka st., 3а; Krasnoyarsk
A. V. Trubkin
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Aleksey V. Trubkin
660022; Partizana Zheleznyaka st., 3а; Krasnoyarsk
A. O. Gavrilova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of Minzdrav of Russia
Russian Federation
Russian Federation
Anna O. Gavrilova
660022; Partizana Zheleznyaka st., 1; Krasnoyarsk
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