Aerobic exercise capacity of healthy young men with the early repolarization phenomenon
https://doi.org/10.18699/SSMJ20210213
Abstract
Data on the performance of individuals with the early repolarization phenomenon (ERP) are contradictory. Aim of the study was to investigate the aerobic physical performance of individuals with ERP. Material and methods. 536 healthy men aged 18–45 years, who do not have contraindications to perform a load test according to physical, laboratory and instrumental examination (ECG, spirometry, echocardiography, clinical blood analysis), and who reached the VO2max during cardiopulmonary exercise testing were included in the study. We compared physical performance of groups formed on the basis of ECG data: the main group - persons with ERP (113 people) and the control group-persons without ERP (423 people). Results. In the group with ERP, the VO2max, cardiac output, oxygen pulse and stroke volume at peak load were lower than in the group without ERP, by 5.8 % (p=0.03), 9.2 % (p=0.05), 7.2 % (p=0.01) and 8.9 % (p=0.04). When compared to echocardiography data, the final systolic size of the left ventricle in the group with ERP was 12.6 % larger than in the group without ERP (p=0.03). Conclusion. In individuals with ERP, a decrease in cardiac output was detected, which may be associated with a relative deterioration in left ventricle systolic function and may affect the aerobic physical performance. The described differences were revealed only after removing the influence of anthropometric, spirometric and laboratory indicators.
About the Authors
M. V. Kabanov
State Science Research Institute of Applied Problems
Russian Federation
Russian Federation
Mikhail V. Kabanov
191167, Saint-Petersburg, Obvodnogo kanala emb., 27
V. N. Nosov
State Science Research Institute of Applied Problems
Russian Federation
Russian Federation
Victor N. Nosov, doctor of medical sciences
191167, Saint-Petersburg, Obvodnogo kanala emb., 27
M. M. Galagudza
Almazov National Medical Research Centre of Minzdrav of Russia
Russian Federation
Russian Federation
Mikhail M. Galagudza, doctor of medical sciences, professor, corresponding member of RAS
197341, Saint-Petersburg, Akkuratov str., 2
E. A. Demchenko
Almazov National Medical Research Centre of Minzdrav of Russia
Russian Federation
Russian Federation
Elena A. Demchenko, doctor of medical sciences
197341, Saint-Petersburg, Akkuratov str., 2
References
1. Ахмедов Н.А. Синдром ранней реполяризации и функциональное состояние сердца у жителей Азии, Африки и Латинской Америки. Кардиология. 1986; 26 (6): 63–65. Akhmedov N.A. Early repolarization syndrome and functional condition of heart at inhabitants of Asia, Africa and Latin America. Kardiologiya = Cardiology. 1986; 26 (6): 63–65. [In Russian]
2. Sethi K.K., Sethi K., Chutani S.K. Early repolarisation and J wave syndromes. Indian Heart Journal. 2014; 66 (4): 443–452. doi: 10.1016/j.ihj.2014.06.002
3. Чичкова М.А., Светличкина А.А., Ковалева Н.А. Электрокардиографический синдром ранней реполяризации желудочков как прогностический критерий аритмий сердца у профессиональных спортсменов. Инновационные технологии в науке и образовании. 2016; 1 (5): 83–86. Chichkova M.A., Svetlichkina A.A., Kovaleva N.A. Electrocardiographic early repolarization syndrome as predictive criterion of arrhythmias of heart at professional athletes. Innovatsionnye tekhnologii v nauke i obrazovanii = Innovative Technologies in Science and Education. 2016; 1 (5): 83–86. [In Russian]
4. Wasserburger R.D., Alt W.I. The normal RS-T segment elevation. Am. J. Cardiol. 1961; 8: 184–192. doi: 10.1016/0002-9149(61)90204-1
5. Ker J., du`Toit L. The accessory papillary muscle with inferior J-waves – peculiarity or hidden danger? Cardiovasc. Ultrasound. 2009; 7: 50. doi: 10.1186/1476-7120-7-50
6. Boineau J.P. The early repolarization variant - normal or a marker of heart disease in certain subjects. J. Electrocardiol. 2007; 4 (1): 11–16. doi: 10.1016/j.jelectrocard.2006.04.002
7. Burashnikov E., Pfeiffer R., BarajasMartinez H., Delpón E., Hu D., Desai M., Borggrefe M., Häissaguerre M., Kanter R., Pollevick G.D., Guerchicoff A., Laiño R., Marieb M., Nademanee K., Nam G.B., Robles R., Schimpf R., Stapleton D.D., Viskin S., Winters S., Wolpert C., Zimmern S., Veltmann C., Antzelevitch C. Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death. Heart Rhythm. 2010; 7 (12): 1872–1882. doi: 10.1016/j.hrthm.2010.08.026
8. Wanatabe H., Minamito T. Role of mutation L-type calcium chanel genes in Brugada Syndrome, early repolarization syndrome, and idiopathic ventricular fibrillation associated with right bundle branch block. Circ. J. 2013; 77 (7): 1689–1690. doi: 10.1253/circj.cj-13-0641
9. Mohrman D.E., Heller L. Cardiovascular physiology. 7-th ed. Philadelphia: The McGraw-Hill Companies, 2010. 304 p.
10. Бобров А.Л., Бойцов С.А. Состояние центральной гемодинамики при синдроме ранней реполяризации. Вестн. аритмол. 2001; (22): 30–33. Bobrov A.L., Boytsov S.A. State of central hemodynamics in early repolarization syndrome. Vestnik aritmologii = Journal of Arrhythmology. 2001; (22): 30–33. [In Russian]
11. Exercise testing for primary care and sports medicine physicians. Eds. C.H. Evans, R.D. White. New York: Springer-Verlag, 2009. 240 р.
12. Obeyesekere M.N., Krahn A.D. Early repolarisation-what should the clinician do? Arrhythm. Electrophysiol. Review. 2015; 4 (2): 96–99. doi: 10.15420/aer.2015.04.02.96
13. Konopka M., Burkhard-Jagodzińska K., Anioł-Strzyżewska K., Krуl W., Klusiewicz A., Chwalbińska A., Pokrywka A., Sitkowski D., Dłużniewski M., Braksator W. Prevalence and determinants of the early repolarisation pattern in a group of young high endurance rowers. Kardiol. Pol. 2016; 74 (3): 289–299. doi: 10.5603/KP.a2015.0133
14. Guo S., Fraser M.W. Propensity score analysis: statistical methods and applications. 2nd ed. SAGE Publications, 2014. 448 р.
15. Antzelevitch C., Gan-Xin Y., Ackerman M.J., Borggrefe M., Corrado D., Guo J., Gussak I., Hasdemir C., Horie M., Huikuri H., Ma C., Morita H., Nam G.B., Sacher F., Shimizu W., Viskin S., Wilde A.M. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Heart Rhythm. 2016; 13 (10): 295–324. doi: 10.1016/j.hrthm.2016.05.024
16. Antzelevitch C., Yan G.X. J wave syndromes. Heart Rhythm. 2010; 7: 549–558. doi: 10.1016/j.hrthm.2009.12.006
17. Badano L.P., Kolias T.J., Muraru D., Abraham T.P., Aurigemma G., Edvardsen T., D’Hooge J., Donal E., Fraser A.G., Marwick T., Mertens L., Popescu B.A., Sengupta P.P., Lancellotti P., Thomas J.D., Voigt J.-U. Standardization of left atrial, right ventricular, and right atrial deformation imaging using two dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry TaskForce to standardize deformationimaging. Eur. Heart J. Cardiovasc. Imaging. 2018; 19 (6): 591–600 doi:10.1093/ehjci/jey042
18. Кропотов С.П., Кабанов М.В., Мордовин И.С., Зайцева А.В., Головина А.С. Нагрузочные протоколы при тестировании физической работоспособности методом спироэргометрии. Биотехносфера. 2014; 31–32 (1-2): 12–17. Kropotov S.P., Kabanov M.V., Mordovin I.S., Zaytseva A.V., Golovina A.S. Workload protocols for CPET. Biotechnosfera = Biotechnosphere. 2014; 31–32 (1-2): 12–17.
19. Wasserman K., Hansen J.E., Sietsema K.E., Sue D.Y., Stringer W.W. Principles of exercise testing and interpretation: including pathophysiology and clinical applications. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2011. 572 p.
20. Stringer W., Hansen J., Wasserman K. Cardiac output estimated non-invasively from oxygen uptake (VO2) during exercise. J. Appl. Physiol. 1997; 82 (3): 908–912. doi: 10.1152/jappl.1997.82.3.908
21. Cooper C.B., Storer T.W. Exercise testing and interpretation a practical approach. Cambridge: Cambridge university press, 2004. 278 p.
Review
For citations:
Kabanov M.V., Nosov V.N., Galagudza M.M., Demchenko E.A. Aerobic exercise capacity of healthy young men with the early repolarization phenomenon. Сибирский научный медицинский журнал. 2021;41(2):92-100. (In Russ.) https://doi.org/10.18699/SSMJ20210213
Views:
401
Email this article 