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Витамин D (стероидный гормон) и заболевания нервной системы (обзор литературы)

https://doi.org/10.15372/SSMJ20200503

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Аннотация

Представлен обзор публикаций по витамину D, его роли в развитии и патогенезе хронических заболеваний нервной системы. Предмет: зависимость развития хронических заболеваний нервной системы от уровня витамина D. Методы: поиск статей в базе данных PubMed, а также через отечественные электронные ресурсы по тегам vitamin D (витамин D), brain diseases (заболевания головного мозга), chronic nervous system diseases (хронические заболевания нервной системы), Parkinson’s disease (болезнь Паркинсона), Alzheimer’s disease (болезнь Альцгеймера), multiple sclerosis (рассеянный склероз), schizophrenia (шизофрения). Результаты. Витамин D, будучи стероидным гормоном, оказывает стимулирующее влияние на мозговую активность как у эмбриона, так и у взрослого индивида; регулирует деятельность нейронных кругов, а также двигательное и эмоциональное поведение. Низкие уровни витамина D в плазме крови обнаружены у пациентов с болезнью Паркинсона, болезнью Альцгеймера, рассеянным склерозом, шизофренией, расстройством аутистического спектра и при нарушениях сна. Обсуждение. Данные представленных современных исследований противоречивы, необходимо дальнейшее изучение значимости гиповитаминоза витамина D для манифестации хронических заболеваний нервной системы и их прогрессирования, а также эффективности препаратов витамина D у пациентов с хронической патологией нервной системы.

Об авторах

Д. А. Новотный
Областной центр экстрапирамидных заболеваний с кабинетом ботулинотерапии
Россия

Денис Александрович Новотный 

630099, г. Новосибирск, ул. Серебренниковская, 42



Н. Г. Жукова
Сибирский государственный медицинский университет Минздрава России
Россия

Наталья Григорьевна Жукова, д.м.н.

634050, г. Томск, Московский тракт, 2



Л. П. Шперлинг
Областной центр экстрапирамидных заболеваний с кабинетом ботулинотерапии
Россия

Лариса Павловна Шперлинг, к.м.н. 

630099, г. Новосибирск, ул. Серебренниковская, 42



В. А. Столярова
Сибирский государственный медицинский университет Минздрава России
Россия

Валентина Александровна Столярова, к.м.н. 

634050, г. Томск, Московский тракт, 2



И. А. Жукова
Сибирский государственный медицинский университет Минздрава России
Россия

Ирина Александровна Жукова, к.м.н. 

634050, г. Томск, Московский тракт, 2



А. Е. Агашева
Сибирский государственный медицинский университет Минздрава России
Россия

Анна Евгеньевна Агашева

634050, г. Томск, Московский тракт, 2



С. В. Штаймец
Сибирский государственный медицинский университет Минздрава России
Россия

Станислав Викторович Штаймец 

634050, г. Томск, Московский тракт, 2



О. А. Дружинина
Областной центр экстрапирамидных заболеваний с кабинетом ботулинотерапии
Россия

Оксана Аркадьевна Дружинина 

630099, г. Новосибирск, ул. Серебренниковская, 42



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Для цитирования:


Новотный Д.А., Жукова Н.Г., Шперлинг Л.П., Столярова В.А., Жукова И.А., Агашева А.Е., Штаймец С.В., Дружинина О.А. Витамин D (стероидный гормон) и заболевания нервной системы (обзор литературы). Сибирский научный медицинский журнал. 2020;40(5):24-37. https://doi.org/10.15372/SSMJ20200503

For citation:


Novotnyy D.A., Zhukova N.G., Shperling L.Р., Stolyarova V.A., Zhukova I.A., Agasheva A.E., Shtaimets S.V., Druzhinina O.A. Vitamin D (steroid hormone) and the nervous system diseases (literature review). Siberian Scientific Medical Journal. 2020;40(5):24-37. (In Russ.) https://doi.org/10.15372/SSMJ20200503

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