On the impact of the COVID-19 pandemic on the мanifestations of aging

O. N. Ergashev; U. R. Saginbaev; I. M. Kobelev

doi:10.18699/SSMJ20250615

On the impact of the COVID-19 pandemic on the мanifestations of aging

O. N. Ergashev, U. R. Saginbaev, I. M. Kobelev

https://doi.org/10.18699/SSMJ20250615

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Abstract

The COVID-19 pandemic has affected many aspects of human life, including accelerated aging of the population. Numerous scientific papers indicate the negative impact of SARS-CoV-2 on health, manifested in a number of changes: from shortening of telomeres and an increase in neurodegenerative diseases to cognitive impairment, depression and an increased risk of cardiovascular diseases, including myocarditis and arrhythmia. In addition, there are problems withcoagulation, changes in the expression of the angiotensin-converting enzyme 2 gene, signs of early vascular aging, early immunological aging, metabolic syndrome and external manifestations of premature aging. The list of consequences of COVID-19 is constantly expanding, including changes in blood biochemistry. In this regard, it is imperative to study the mechanisms underlying these changes and develop prevention strategies to maintain healthy aging in the post-COVID era. These features can be taken into account when developing projects to support the older generation.

Keywords

COVID-19, premature aging, accelerated aging, telomeres, biological age, inflammaging, aging rate, population

About the Authors

O. N. Ergashev

Institute of Experimental Medicine; I.P. Pavlov First St. Petersburg State Medical University
Russian Federation

Oleg N. Ergashev - doctor of medical sciences, professor.

197022, Saint-Petersburg, Acad. I.P. Pavlov st., 12D; 197022, Saint-Petersburg, L. Tolstoy st., 6-8

U. R. Saginbaev

Institute of Experimental Medicine; I.P. Pavlov First St. Petersburg State Medical University
Russian Federation

Ural R. Saginbaev - candidate of biological sciences.
197022, Saint-Petersburg, Acad. I.P. Pavlov st., 12D; 197022, Saint-Petersburg, L. Tolstoy st., 6-8

I. M. Kobelev

Saint-Petersburg Institute of Bioregulation and Gerontology Ivan M. Kobelev - candidate of biological sciences.
Russian Federation

Ivan M. Kobelev - candidate of biological sciences.

197110, Saint-Petersburg, Dynamo ave., 3

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