An experimental model of endoscopic argon plasma coagulation in liquid medium
A. Ya. Ilkanich,
V. V. Darvin,
A. V. Satinov,
A. V. Oganian,
M. G. Ryzhikov,
A. A. Remeev,
A. Yu. Krysov,
A. N. Nazarov,
D. K. Kasyanov,
A. A. Rosinskii,
A. A. Mamatislamov,
S. N. Artamonova https://doi.org/10.18699/SSMJ20240513
Abstract
The aim of the research was to investigate the effect of argon plasma coagulation on the wall of the gastrointestinal tract in experiment. Material and methods. A method of endoscopic argon plasma coagulation in a liquid medium was developed to eliminate the shortcomings of the standard technology. Rabbits, divided into two groups, were used as experimental animals; the developed technology of argon plasma coagulation in a liquid medium was applied in the treatment group, while the standard technology of argon plasma coagulation was used in the control group. Gastroscopy, with focal application of argon plasma coagulation followed by morphological examination of the coagulation zones after 1 hour, 1 day, 3 days, and 5 days, was performed. Results. Analysis of morphological sections indicates that when using argon plasma coagulation in a liquid medium, the depth of coagulation impact on biological tissues decreases, as well as the severity of inflammatory changes, resulting in faster reparative changes. The obtained results may be of interest for further clinical-experimental research and implementation into clinical practice of modifications of endoscopic argon plasma coagulation.
About the Authors
A. Ya. Ilkanich
Surgut State University
Russian Federation
Russian Federation
Andrey Ya. Ilkanich, doctor of medical sciences, professor
V. V. Darvin
Surgut State University
Russian Federation
Russian Federation
Vladimir V. Darvin, doctor of medical sciences, professor
A. V. Satinov
Nizhnevartovsk District Clinical Hospital
Russian Federation
Russian Federation
Aleksei V. Satinov
628606, Nizhnevartovsk, Lenina st., 18
A. V. Oganian
Nizhnevartovsk District Clinical Hospital
Russian Federation
Russian Federation
Armen V. Oganian
628606, Nizhnevartovsk, Lenina st., 18
M. G. Ryzhikov
Surgut State University
Russian Federation
Russian Federation
Mikhail G. Ryzhikov
628400, Surgut, Lenina st., 1
A. A. Remeev
Surgut State University
Russian Federation
Russian Federation
Artem A. Remeev
628400, Surgut, Lenina st., 1
A. Yu. Krysov
Surgut State University
Russian Federation
Russian Federation
Artem Yu. Krysov
628400, Surgut, Lenina st., 1
A. N. Nazarov
Surgut State University
Russian Federation
Russian Federation
Alexandr N. Nazarov
628400, Surgut, Lenina st., 1
D. K. Kasyanov
Surgut State University
Russian Federation
Russian Federation
Dmitriy K. Kasyanov
628400, Surgut, Lenina st., 1
A. A. Rosinskii
Surgut State University
Russian Federation
Russian Federation
Aleksei A. Rosinskii
628400, Surgut, Lenina st., 1
A. A. Mamatislamov
Surgut State University
Russian Federation
Russian Federation
Abduvali A. Mamatislamov
628400, Surgut, Lenina st., 1
S. N. Artamonova
Surgut State University
Russian Federation
Russian Federation
Svetlana N. Artamonova
628400, Surgut, Lenina st., 1
References
1. Valeev M.V., Timerbulatov Sh.V. Gastroduodenal bleedings. Upper gastrointestinal bleeding. analysis of the results of treatment in a district hospital. Vestnik Natsional’nogo mediko-khirurgicheskogo tsentra imeni Nikolaya Ivanovicha Pirogova = Bulletin of Pirogov National Medical and Surgical Center. 2020;15(1):39–42. [in Russian]. doi: 10.25881/BPNMSC.2020.61.63.007
2. González-González J.A., García-Compean D., Vázquez-Elizondo G., Garza-Galindo A., Jáquez-Quintana J.O., Maldonado-Garza H. Nonvariceal upper gastrointestinal bleeding in patients with liver cirrhosis. Clinical features, outcomes and predictors of in-hospital mortality. A prospective study. Ann. Hepatol. 2011;10(3):287–295.
3. Siau K., Chapman W., Sharma N., Tripathi D., Iqbal T., Bhala N. Management of acute upper gastrointestinal bleeding: an update for the general physician. J. R. Coll. Physicians. Edinb. 2017;47(3):218–230. doi: 10.4997/JRCPE.2017.303
4. Kim J.W., Jang J.Y., Lee C.K., Shim J.J., Chang Y.W. Comparison of hemostatic forceps with soft coagulation versus argon plasma coagulation for bleeding peptic ulcer–a randomized trial. Endoscopy. 2015;47(8):680–687. doi: 10.1055/s-0034-1391565
5. Grund K. E., Storek D., Farin G. Endoscopic argon plasma coagulation (APC) first clinical experiences in flexible endoscopy. Endosc. Surg. Allied Techno. 1994;2(1):42–46.
6. Farin G., Grund K. E. Technology of argon plasma coagulation with particular regard to endoscopic applications. Endosc. Surg. Allied Techno. 1994;2(1):71–77.
7. World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;27;310(20):2191–2194. doi: 10.1001/jama.2013.281053
Review
For citations:
Ilkanich A.Ya., Darvin V.V., Satinov A.V., Oganian A.V., Ryzhikov M.G., Remeev A.A., Krysov A.Yu., Nazarov A.N., Kasyanov D.K., Rosinskii A.A., Mamatislamov A.A., Artamonova S.N. An experimental model of endoscopic argon plasma coagulation in liquid medium. Сибирский научный медицинский журнал. 2024;44(5):111-118. (In Russ.) https://doi.org/10.18699/SSMJ20240513
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