Possibilities of the ultrasound method in the diagnosis of pathology of the septal region. Literature review and clinical cases
https://doi.org/10.18699/SSMJ20230404
Abstract
Disorder of the formation of the cavum septum pellucidum (CSP) occurs in a wide range of pathologies of the brain. Its identification from 18 to 37 weeks is a necessary rule of prenatal screening, which must also be performed in postnatal studies of premature infants. Unimaged CSP should be considered as a potential indicator of cerebral dysfunction and such severe malformations as agenesis (dysgenesis) of the corpus callosum, holoprosencephaly (HPE), schizencephaly, Aicardi syndrome, hydrocephalus and septo-optic dysplasia (SOD). A special place in the differential diagnosis of unimaged CSP is represented by SOD, lobar HPE, and its mild subtype - septopreoptic HPE. The literature describes the isolated absence of SP, without finding other signs related to HPE or SOD, as a variant of development. However, the neurological outcome in these children varies from normal to delayed development of the nervous system by different degrees, so this statement remains controversial. The article discusses in detail the anatomy, physiology, pathology of the septal region, the role of echographic studies in the antenatal and postnatal periods, and the correlation of the detected changes with the clinical picture.
About the Authors
S. Yu. Cherdantseva
Altai Regional Clinical Perinatal Center
Russian Federation
Russian Federation
Svetlana Yu. Cherdantseva
656045, Barnaul, Fomina st., 154
E. B. Olkhova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov of Minzdrav of Russia; Moscow Clinical Municipal Children Hospital St. Vladimir
Russian Federation
Russian Federation
Elena B. Olkhova, doctor of medical sciences, professor
656045, Barnaul, Fomina st., 154
127473, Moscow, Delegatskaya st., 20/1
Yu. E. Cherdantseva
Sechenov First Moscow State Medical University of Minzdrav of Russia
Russian Federation
Russian Federation
Yulia E. Cherdantseva
119992, Moscow, Trubetskaya st., 8/2
O. P. Kanailova
State Novosibirsk Regional Clinical Hospital
Russian Federation
Russian Federation
Ol’ga P. Kanailova
630087 Novosibirsk, Nemirovicha-Danchenko st., 130
N. V. Gorbacheva
Altay State Medical University of Minzdrav of Russia
Russian Federation
Russian Federation
Natal’ya V. Gorbacheva
656038, Barnaul, Lenina ave., 40
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Review
For citations:
Cherdantseva S.Yu., Olkhova E.B., Cherdantseva Yu.E., Kanailova O.P., Gorbacheva N.V. Possibilities of the ultrasound method in the diagnosis of pathology of the septal region. Literature review and clinical cases. Сибирский научный медицинский журнал. 2023;43(4):44-54. (In Russ.) https://doi.org/10.18699/SSMJ20230404
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