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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sibmed</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский научный медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Сибирский научный медицинский журнал</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2410-2512</issn><issn pub-type="epub">2410-2520</issn><publisher><publisher-name>ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15372/SSMJ20180506</article-id><article-id custom-type="elpub" pub-id-type="custom">sibmed-64</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ ХОРИОРЕТИНАЛЬНОГО КРОВОТОКА У БОЛЬНЫХ С ОТКРЫТОУГОЛЬНОЙ ГЛАУКОМОЙ</article-title><trans-title-group xml:lang="en"><trans-title>FEATURES OF CHORIORETINAL BLOOD FLOW IN PATIENTS WITH OPEN-ANGLE GLAUCOMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">zhukswetlana@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юрьева</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuryeva</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">tnyurieva@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Помкина</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pomkina</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">xii.83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грищук</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Grishchuk</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">angrish@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МНТК «Микрохирургия глаза» имени академика С.Н. Федорова Минздрава России, Иркутский филиал</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk Branch</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>МНТК «Микрохирургия глаза» имени академика С.Н. Федорова Минздрава России, Иркутский филиал; Иркутская государственная медицинская академия последипломного образования - филиал Российской медицинской академии непрерывного профессионального образования Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk Branch; Irkutsk State Medical Academy of Postgraduate Education, Branch of the Russian Medical Academy of Continuing Vocational Education of Minzdrav of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2019</year></pub-date><volume>38</volume><issue>5</issue><fpage>38</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жукова С.И., Юрьева Т.Н., Помкина И.В., Грищук А.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Жукова С.И., Юрьева Т.Н., Помкина И.В., Грищук А.С.</copyright-holder><copyright-holder xml:lang="en">Zhukova S.I., Yuryeva T.N., Pomkina I.V., Grishchuk A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://sibmed.elpub.ru/jour/article/view/64">https://sibmed.elpub.ru/jour/article/view/64</self-uri><abstract><p>Цель исследования - оценить особенности гемодинамики при колебании внутриглазного давления (ВГД), выявить дифференциально-диагностические критерии адекватного мониторирования течения глаукомы по данным оптической когерентной томографии с функцией ангиографии. Материал и методы. Обследовано 25 больных (25 глаз) с гипертензивной первичной открытоугольной глаукомой. В объем исследования включена оптическая когерентная томография сетчатки и диска зрительного нерва с функцией ангиографии. Пациентам клинической группы выполнена фистулизирующая операция непроникающего типа с последующей лазерной гониопунктурой. Обследование проводилось перед операцией, в раннем послеоперационном периоде, через один и три месяца после хирургического вмешательства. Группу контроля составили 12 человек (24 глаза) без офтальмопатологии соответствующего возраста и пола. Результаты и их обсуждение. Полученные результаты свидетельствуют о роли регионарной гемодинамики в формировании глаукомной нейрооптикопатии. Выявленные гемодинамические нарушения в виде уменьшения толщины хориоидеи, снижения плотности радиального перипапиллярного, поверхностного сосудистого сплетений и соответствующие им глаукомные изменения диска зрительного нерва, слоя нервных волокон и ганглиозного комплекса сетчатки позволяют говорить о гипоперфузии, обусловленной снижением метаболических потребностей атрофированной ткани. Хирургические вмешательства, применяемые при лечении больных глаукомой, приводят к улучшению параметров кровотока. Ретинальные и хориоидальные сосуды по-разному реагируют на колебания внутриглазного давления, что указывает на различный механизм адаптации сосудистой системы глаза в ответ на изменение офтальмотонуса и необходимость определения индивидуальной нормы внутриглазного давления.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the study was to evaluate the features of hemodynamics in patients with intraocular pressure (IOP) fluctuations, to reveal differential diagnostic criteria for adequate monitoring of glaucoma course according to optical coherence tomography (OCT) with the function of angiography. Material and methods. 25 patients (25 eyes) with hypertensive POAG were examined. The study included OCT of the retina and optic disk with the function of angiography. Patients of the clinical group underwent a non-penetrating fistulizing operation followed by laser goniopuncture. The examination was performed before the operation, in the early postoperative period, 1 and 3 months after the surgical intervention. The control group was 12 people (24 eyes) without ophthalmic pathology of the corresponding age and sex. Results and discussion. The obtained results testify to the role of regional hemodynamics in the formation of glaucoma neuroopticopathy. The revealed hemodynamic disturbances in the form of the decrease in the thickness of the choroid, decrease in the density of the radial peripapillary, superficial vascular plexus, and the corresponding glaucomatous changes in the optic disk, the layer of nerve fibers and the ganglionic retina complex, allow speaking about hypoperfusion caused by the decrease in the metabolic needs of atrophied tissue. Surgical interventions used in the treatment of patients with glaucoma lead to an improvement in blood flow parameters. Retinal and choroidal vessels respond differently to intraocular pressure fluctuations, which indicate different mechanism of adaptation of the eye’s vascular system in response to the change in the ophthalmotonus. In this connection, the question arises of the need to determine the individual intraocular pressure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ОКТ-диагностика глаукомы</kwd><kwd>ОКТ-ангиография</kwd><kwd>слой нервных волокон сетчатки</kwd><kwd>ганглиозный комплекс сетчатки</kwd><kwd>ретинальный кровоток</kwd></kwd-group><kwd-group xml:lang="en"><kwd>OCT-diagnosis of glaucoma</kwd><kwd>OCT-angiography</kwd><kwd>retinal nerve fiber layer</kwd><kwd>retinal ganglion cell complex</kwd><kwd>retinal blood flow</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Национальное руководство по глаукоме для практикующих врачей, 3-е изд., испр. и доп. / ред. Е.А. 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