sibmedСибирский научный медицинский журналСибирский научный медицинский журнал2410-25122410-2520ИЦиГ СО РАН10.15372/SSMJ20200410sibmed-455Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEАссоциация коморбидной соматической патологии с индексом массы тела и типами распределения жира у мужчинAssociation of comorbid somatic pathology with fat distribution type and body mass index in menhttps://orcid.org/0000-0001-8486-3185ЯнковскаяС. В.IankovskaiaS. V.

Светлана Валерьевна Янковская

Svetlana V. Iankovskaia

svetlanaiankovskaia@gmail.comhttps://orcid.org/0000-0003-4723-0666НовиковаЕ. Г.NovikovaE. G.

Елена Геннадьевна Новикова, к.м.н.

Elena G. Novikova, candidate of medical science

https://orcid.org/0000-0002-9041-2687ЕпанчинцеваЕ. А.EpanchintsevaE. A.

Елена Александровна Епанчинцева, к.м.н.

Elena A. Epanchintseva, candidate of medical sciences

https://orcid.org/0000-0002-4579-425XПинхасовБ. Б.PinkhasovB. B.

Борис Борисович Пинхасов, д.м.н.

Boris B. Pinkhasov, doctor of medical sciences

https://orcid.org/0000-0003-4534-7289СелятицкаяВ. Г.SelyatitskayaV. G.

Вера Георгиевна Селятицкая, д.б.н., проф.

Vera G. Selyatitskaya, doctor of biological sciences, professor

ФИЦ фундаментальной и трансляционной медициныРоссияFederal Research Center for Fundamental and Translational MedicineRussian Federation2020280820204047077Copyright © Янковская С.В., Новикова Е.Г., Епанчинцева Е.А., Пинхасов Б.Б., Селятицкая В.Г., 20202020Янковская С.В., Новикова Е.Г., Епанчинцева Е.А., Пинхасов Б.Б., Селятицкая В.Г.Iankovskaia S.V., Novikova E.G., Epanchintseva E.A., Pinkhasov B.B., Selyatitskaya V.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://sibmed.elpub.ru/jour/article/view/455

Цель исследования – изучить влияние избыточной массы тела, ожирения и типа распределения жира на отягощенность коморбидной соматической патологией мужчин – пациентов клиники терапевтического профиля. Материал и методы. На базе терапевтической клиники в период с 2018 по 2019 г. проведено обсервационное одномоментное исследование 216 пациентов мужского пола в возрасте от 22 до 78 лет, госпитализированных в плановом порядке. У мужчин были измерены рост, масса тела, окружности талии (ОТ) и бедер (ОБ), рассчитаны величины отношения ОТ/ОБ и индекса массы тела (ИМТ). Выраженность клинических признаков старения оценена при помощи опросника AMS, коморбидная отягощенность – посредством анализа историй болезни с использованием шкалы CIRS. Результаты и их обсуждение. Показано, что избыточная МТ и ожирение приводят к увеличению отягощенности по сердечно-сосудистой, эндокринной патологии и общей коморбидности у мужчин. Влияние типа распределения жира различно при разном ИМТ пациентов. При нормальной МТ верхний тип распределения жира приводит к увеличению коморбидной отягощенности только по патологии сосудов, при избыточной МТ – по патологии сосудов и эндокринной системы, при ожирении – по патологии сосудов, сердца и общей коморбидной отягощенности. Заключение. Избыточная МТ и ожирение ассоциированы с увеличением отягощенности по сердечно-сосудистой, эндокринной патологии и общей коморбидной отягощенности у мужчин, а верхний тип распределения жира выступает в качестве самостоятельного фактора коморбидной отягощенности по сосудистой патологии вне зависимости от ИМТ.

The purpose of the study was to investigate the effect of overweight, obesity and fat distribution type on the severity of comorbid somatic pathology in men. Material and methods. 216 men, aged from 22 to 78 years, who were patients of therapeutic clinic from 2018 to 2019 years, were observed. Height, body weight, waist (WC) and hip (HC) circumference were measured using standard anthropometric procedures, and then WC/HC and body mass index (BMI) were calculated. Clinical signs of aging were estimated by using the AMS questionnaire. The CIRS was scored from the medical records after hospitalization. Results and discussion. It was shown that overweight and obesity increase the burden of cardiovascular, endocrine and general comorbidity in men. Nevertheless, the burden of cardiovascular pathology did not differ between overweight and obesity men. The contribution of fat distribution type in separate BMI-groups is different. The upper fat distribution type in normal body weight increases the burden of vascular pathology, in overweight – vascular pathology and endocrine system, in obesity – cardiovascular pathology, and general comorbidity in men. Conclusion. Thus, the BMI ≥ 25 kg/m2 is associated with an increase burden of cardiovascular, endocrine and general comorbidity and upper fat distribution type increases the burden of vascular pathology in men.

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The authors declare that there are no conflicts of interest present.