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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sibmed</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский научный медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Сибирский научный медицинский журнал</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2410-2512</issn><issn pub-type="epub">2410-2520</issn><publisher><publisher-name>ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18699/SSMJ20240419</article-id><article-id custom-type="elpub" pub-id-type="custom">sibmed-1635</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Эпидемиологические и клинические особенности кори на примере вспышки заболевания в Пензенской области</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological and clinical features of measles on the example of an outbreak in the Penza region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курмаева</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurmaeva</surname><given-names>J. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курмаева Джамиля Юсуповна, к.м.н.</p><p>440052, г. Пенза, ул. Куйбышева, 33а</p><p>440026, г. Пенза, ул. Лермонтова, 3  </p></bio><bio xml:lang="en"><p>Jamilya Yu. Kurmaeva, candidate of medical sciences</p><p>440052, Penza, Kuibysheva st., 33a</p><p>440026, Penza, Lermontova st., 3 </p></bio><email xlink:type="simple">svmp@penzadom.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афонин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Afonin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афонин Александр Викторович</p><p>440052, г. Пенза, ул. Куйбышева, 33а</p></bio><bio xml:lang="en"><p>Alexandr V. Afonin</p><p>440052, Penza, Kuibysheva st., 33a</p></bio><email xlink:type="simple">svmp@penzadom.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбалкин</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybalkin</surname><given-names>S. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рыбалкин Сергей Борисович, к.м.н.</p><p>440052, г. Пенза, ул. Куйбышева, 33а</p><p>440026, г. Пенза, ул. Лермонтова, 3  </p></bio><bio xml:lang="en"><p>Sergey B. Rybalkin, candidate of medical sciences</p><p>440052, Penza, Kuibysheva st., 33a</p><p>440026, Penza, Lermontova st., 3 </p></bio><email xlink:type="simple">svmp@penzadom.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2175-5547</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельников</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikov</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельников Виктор Львович, д.м.н.</p><p>440026, г. Пенза, ул. Лермонтова, 3</p></bio><bio xml:lang="en"><p>Victor L. Melnikov, doctor of medical sciences</p><p>440026, Penza, Lermontova st., 3 </p></bio><email xlink:type="simple">meidpgumi@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3385-4104</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никольская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolskaya</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никольская Марина Викторовна, к.м.н.</p><p>440026, г. Пенза, ул. Лермонтова, 3</p></bio><bio xml:lang="en"><p>Marina V. Nikolskaya, candidate of medical sciences</p><p>440026, Penza, Lermontova st., 3 </p></bio><email xlink:type="simple">missmarina1956@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пензенский областной клинический центр специализированных видов медицинской помощи; Пензенский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Penza regional Clinical Сenter of Specialized Types of Medical Care; Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Пензенский областной клинический центр специализированных видов медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Penza regional Clinical Сenter of Specialized Types of Medical Care</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Пензенский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>08</month><year>2024</year></pub-date><volume>44</volume><issue>4</issue><fpage>168</fpage><lpage>173</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Курмаева Д.Ю., Афонин А.В., Рыбалкин С.Б., Мельников В.Л., Никольская М.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Курмаева Д.Ю., Афонин А.В., Рыбалкин С.Б., Мельников В.Л., Никольская М.В.</copyright-holder><copyright-holder xml:lang="en">Kurmaeva J.Y., Afonin A.V., Rybalkin S.B., Melnikov V.L., Nikolskaya M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://sibmed.elpub.ru/jour/article/view/1635">https://sibmed.elpub.ru/jour/article/view/1635</self-uri><abstract><p>В настоящее время во многих странах мира, в том числе и в России, наблюдается рост заболеваемости корью. Одной из причин этого подъема является снижение числа вакцинированных, нарушение схем вакцинации. Цель исследования – изучение эпидемиологических и клинических особенностей кори во время вспышки болезни в Пензенской области в 2023 г. Материал и методы. Проведен ретроспективный анализ 73 медицинских карт больных во время вспышки заболевания в селе Средняя Елюзань Пензенской области в 2023 г. Подтверждение диагноза осуществлялось при выявлении в крови специфического маркера (IgM) методом ИФА. Результаты и их обсуждение. Среди заболевших детей было 67, взрослых – 6. Амбулаторно лечились 36 человек, госпитализировано 37 детей. Среди заболевших корью детей не были привиты против кори 63 ребенка, из них 59 – в связи с отказом родителей от иммунизации. У всех пациентов корь характеризовалась типичными клиническими проявлениями. Среднетяжелые формы заболевания выявлены у 43 детей и 6 взрослых, (67,1 %), легкие – у 24 (32,9 %) детей. Заключение. Характерной особенностью данного заболевания являлось наличие более выраженных симптомов и более длительного катарального периода у детей старших возрастных групп. Благодаря своевременному проведению профилактических и противоэпидемиологических мероприятий очаг удалось локализовать и предотвратить дальнейшее распространение инфекции. Учитывая повторную возможность возникновения вспышек, необходимо улучшать вакцинопрофилактику.</p></abstract><trans-abstract xml:lang="en"><p>Currently, many countries around the world, including Russia, are experiencing an increase in measles morbidity. One of the reasons for this rise is a decrease in the number of vaccinated persons and violation of vaccination schemes. Aim of the study was to investigate of epidemiologic and clinical features of the disease during the measles outbreak in Penza Oblast in 2023. Material and Methods. A retrospective analysis of 73 medical records of patients during the outbreak of the disease in the village of Srednaya Elyuzan, Penza region, in 2023 was performed. The diagnosis was confirmed by detection of specific marker (IgM) in the blood by ELISA. Results and discussion. There were 67 children and 6 adults among those who fell ill. Outpatient treatment was provided to 36 persons, and 37 children were hospitalized. Among the children who contracted measles, 63 children were not immunized against measles, 59 of them due to parents’ refusal to immunize them. In all patients, measles was characterized by typical clinical manifestations. Moderate forms of the disease were detected in 43 children and 6 adults (67.1 %), mild – in 24 (32.9 %) children. Conclusions. A characteristic feature of this disease was the presence of more pronounced symptoms and a longer catarrhal period in older children. Thanks to timely preventive and anti-epidemiological measures, the outbreak was localized and further spread of the infection was prevented. Given the repeated possibility of outbreaks, it is necessary to improve vaccine prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>корь</kwd><kwd>заболеваемость</kwd><kwd>клинические особенности</kwd><kwd>противоэпидемиологические мероприятия</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>measles</kwd><kwd>morbidity</kwd><kwd>clinical features</kwd><kwd>anti-epidemic measures</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клиническое руководство по инфекционным болезням (2-е изд.). Ред. А.В. Горелов. М.: Медконгресс, 2022. 345–350.</mixed-citation><mixed-citation xml:lang="en">Clinical Guide to Infectious Diseases (2nd ed.) Ed. A.V. Gorelov. 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