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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sibmed</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский научный медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Сибирский научный медицинский журнал</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2410-2512</issn><issn pub-type="epub">2410-2520</issn><publisher><publisher-name>ИЦиГ СО РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18699/SSMJ20230406</article-id><article-id custom-type="elpub" pub-id-type="custom">sibmed-1157</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАТОМИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANATOMY</subject></subj-group></article-categories><title-group><article-title>Морфометрический анализ структур черепа по данным компьютерной томографии у детей в норме и при долихоцефалии</article-title><trans-title-group xml:lang="en"><trans-title>Morphometric analysis of the structures of the skull according to computed tomography data in children in norm and in dolichocephaly</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5554-4588</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаибов</surname><given-names>С. С.-Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaibov</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаибов Сайди Саит-Хусейнович, к.м.н.</p><p>625023, г. Тюмень, ул. Одесская, 54</p><p>625039, г. Тюмень, ул. Мельникайте, 75</p></bio><bio xml:lang="en"><p>Saidi S. Gaibov, candidate of medical sciences</p><p>625023, Tyumen, Odesskaya st., 54</p><p>625039, Tyumen, Melnikaite st., 75</p></bio><email xlink:type="simple">s-stavros@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1317-5219</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарчук</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharchyk</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарчук Екатерина Владимировна, к.м.н.</p><p>625023, г. Тюмень, ул. Одесская, 54</p><p>625039, г. Тюмень, ул. Мельникайте, 75</p></bio><bio xml:lang="en"><p>Ekaterina V. Zacharchyk, candidate of medical sciences</p><p>625023, Tyumen, Odesskaya st., 54</p><p>625039, Tyumen, Melnikaite st., 75</p></bio><email xlink:type="simple">katgor@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4967-6047</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>Д. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobjov</surname><given-names>D. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Воробьев Дмитрий Петрович, к.м.н.</p><p>625023, г. Тюмень, ул. Одесская, 54</p><p>625039, г. Тюмень, ул. Мельникайте, 75</p></bio><bio xml:lang="en"><p>Dmitry P. Vorobyev, candidate of medical sciences</p><p>625023, Tyumen, Odesskaya st., 54</p><p>625039, Tyumen, Melnikaite st., 75</p></bio><email xlink:type="simple">ratr@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет Минздрава России; Областная клиническая больница № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University of Minzdrav of Russia; Regional Clinical Hospital N 2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2023</year></pub-date><volume>43</volume><issue>4</issue><fpage>65</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаибов С.С., Захарчук Е.В., Воробьев Д.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Гаибов С.С., Захарчук Е.В., Воробьев Д.П.</copyright-holder><copyright-holder xml:lang="en">Gaibov S.S., Zakharchyk E.V., Vorobjov D.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://sibmed.elpub.ru/jour/article/view/1157">https://sibmed.elpub.ru/jour/article/view/1157</self-uri><abstract><p>Отмечается повышенный интерес к проблеме оказания помощи детям с деформациями черепа, которые возникают из-за преждевременного закрытия черепных швов и развития краниосиностоза. Оценка краниального дисморфизма при деформациях черепа часто бывает субъективной и остается сложной задачей. Морфометрические исследования при этом – значительный раздел, плохо освещенный в современной научно-практической и справочной медицинской литературе.Материал и методы. Выполнен анализ данных краниометрических измерений, цефалического индекса (CI) по результатам КТ у 24 детей с долихоцефалией (14 мальчиков, 10 девочек) в возрасте 7,4 ± 3,2 мес. (2–12 мес.) и в контрольной группе из 25 детей (15 мальчиков, 9 девочек) в возрасте 7,2 ± 4,8 мес. (2–12 мес.).Результаты. Полученные данные продемонстрировали существенные различия у детей при долихоцефалии и в норме. CI хорошо показывает соотношение линейных размеров черепа в норме и при долихоцефалии. Наиболее значимые различия выявлены при оценке расстояний G-Op, CG-TS, CG-MAI, MAI-MAI, Zg-Zg, Ec-Ec, Br-Ba, при этом при долихоцефалии параметры CG-TS, CG-MAI, MAI-MAI, Br-Ba отражают деформацию основания черепа, а Zg-Zg, Ec-Ec – лицевого скелета.Заключение. Проведенный комплексный морфометрический анализ структур и черепа, основанный на измерениях по точным анатомическим ориентирам, продемонстрировал существенные объективные различия в морфологии черепа у детей в норме и при долихоцефалии. Полученные данные говорят о важности комплексной оценки изменений черепа при всех его формах. Выполнение такого анализа важно для понимания всей полноты морфологических изменений черепа в норме и при патологии.</p></abstract><trans-abstract xml:lang="en"><p>There is an increased interest in the problem of helping children with skull deformities that occur due to premature closure of cranial sutures and the development of craniosynostosis. Assessment of cranial dysmorphism in skull deformities is often subjective and remains a challenge. Morphometric studies are a significant section that is poorly covered in modern scientific, practical and reference medical literature.Material and methods. The analysis of the data of craniometric measurements, of cephalic index (CI) according to the results of computed tomography in 24 children with dolichocephaly (14 boys, 10 girls) at the age of 7.4 ± 3.2 months (2–12 months) and in the control group of 25 children (15 boys, 9 girls) at the age of 7.2 ± 4.8 months (2–12 months).Results. The data showed significant differences in children in norm and in dolichocephaly. CI shows the ratio of the linear dimensions of the skull in normal and dolichocephaly. The most significant differences were revealed when assessing the distances G-Op, CG-TS, CG-MAI, MAI-MAI, Zg-Zg, Ec-Ec, Br-Ba. CG-TS, CG-MAI, MAI-MAI, Br-Ba reflect deformation of the skull base, and Zg-Zg, Ec-Ec – deformation of the facial skeleton in dolichocephaly.Conclusions. A comprehensive morphometric analysis of the skull structures based on precise anatomical landmarks demonstrated objective differences in the morphology of the skull in children with normal conditions and with dolichocephaly. The data indicate the importance of a comprehensive assessment of changes in the skull for all forms of the skull. Carrying out such an analysis is important for understanding all morphological changes in the skull in health and disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лучевая диагностика</kwd><kwd>долихоцефалия</kwd><kwd>краниосиностоз</kwd><kwd>краниометрия</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>radiation diagnostics</kwd><kwd>dolichocephaly</kwd><kwd>craniosynostosis</kwd><kwd>craniometry</kwd><kwd>computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Thiele-Nygaard A.E., Foss-Skiftesvik J., Juhler M. Intracranial pressure, brain morphology and cognitive outcome in children with sagittal craniosynostosis. Childs Nerv. Syst. 2020;36(4):689–695. doi: 10.1007/s00381-020-04502-z</mixed-citation><mixed-citation xml:lang="en">Thiele-Nygaard A.E., Foss-Skiftesvik J., Juhler M. Intracranial pressure, brain morphology and cognitive outcome in children with sagittal craniosynostosis. Childs Nerv. Syst. 2020;36(4):689–695. doi: 10.1007/s00381-020-04502-z</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Lloyd M.S., Buchanan E.P., Khechoyan D.Y. Review of quantitative outcome analysis of cranial morphology in craniosynostosis. J. Plast. Reconstr. Aesthet. Surg. 2016;69(11):1464–1468. doi: 10.1016/j.bjps.2016.08.006</mixed-citation><mixed-citation xml:lang="en">Lloyd M.S., Buchanan E.P., Khechoyan D.Y. Review of quantitative outcome analysis of cranial morphology in craniosynostosis. J. Plast. Reconstr. Aesthet. Surg. 2016;69(11):1464–1468. doi: 10.1016/j.bjps.2016.08.006</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Malde O., Cross C., Lim C.L., Marghoub A., Cunningham M.L., Hopper R.A., Moazen M. Predicting calvarial morphology in sagittal craniosynostosis. Sci. Rep. 2020;10(1):3. doi: 10.1038/s41598-019-55224-5</mixed-citation><mixed-citation xml:lang="en">Malde O., Cross C., Lim C.L., Marghoub A., Cunningham M.L., Hopper R.A., Moazen M. Predicting calvarial morphology in sagittal craniosynostosis. Sci. Rep. 2020;10(1):3. doi: 10.1038/s41598-019-55224-5</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yagain V.K., Pai S.R., Kalthur S.G., Chethan P., Hemalatha I. Study of cephalic index in Indian students. Int. J. Morphol. 2012;30(1):125–129.</mixed-citation><mixed-citation xml:lang="en">Yagain V.K., Pai S.R., Kalthur S.G., Chethan P., Hemalatha I. Study of cephalic index in Indian students. Int. J. Morphol. 2012;30(1):125–129.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Beckett J.S., Pfaff M.J., Diluna M., Steinbacher D.M. Dolichocephaly without sagittal craniosynostosis. J. Craniofac. Surg. 2013;24(5):1713–1715. doi: 10.1097/SCS.0b013e3182a12ece</mixed-citation><mixed-citation xml:lang="en">Beckett J.S., Pfaff M.J., Diluna M., Steinbacher D.M. Dolichocephaly without sagittal craniosynostosis. J. Craniofac. Surg. 2013;24(5):1713–1715. doi: 10.1097/SCS.0b013e3182a12ece</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mewes A.J., Zöllei L., Hüppi P.S., Als H., McAnulty G.B., Inder T.E., Wells W.M., Warfield S.K. Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI. Neuroimage. 2007;36(4):1074–1085. doi: 10.1016/j.neuroimage.2007.04.011</mixed-citation><mixed-citation xml:lang="en">Mewes A.J., Zöllei L., Hüppi P.S., Als H., McAnulty G.B., Inder T.E., Wells W.M., Warfield S.K. Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI. Neuroimage. 2007;36(4):1074–1085. doi: 10.1016/j.neuroimage.2007.04.011</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kochuvareed M.T., Tomy M.G., Chandramohan N., Velayutham M., Sheth J., Sheth F., Janaki V. Prenatal dolichocephaly: sign of trouble? A variant of Miller–Dieker syndrome. Fetal Pediatr. Pathol. 2013;32(4):308–311. doi: 10.3109/15513815.2012.754529</mixed-citation><mixed-citation xml:lang="en">Kochuvareed M.T., Tomy M.G., Chandramohan N., Velayutham M., Sheth J., Sheth F., Janaki V. Prenatal dolichocephaly: sign of trouble? A variant of Miller–Dieker syndrome. Fetal Pediatr. Pathol. 2013;32(4):308–311. doi: 10.3109/15513815.2012.754529</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Marcus J.R., Domeshek L.F., Loyd A.M., Schoenleber J.M., Das R.R., Nightingale R.W., Mukundan S. Use of a three-dimensional, normative database of pediatric craniofacial morphology for modern anthropometric analysis. Plast. Reconstr. Surg. 2009;124(6):2076–2084. doi: 10.1097/PRS.0b013e3181bf7e1b</mixed-citation><mixed-citation xml:lang="en">Marcus J.R., Domeshek L.F., Loyd A.M., Schoenleber J.M., Das R.R., Nightingale R.W., Mukundan S. Use of a three-dimensional, normative database of pediatric craniofacial morphology for modern anthropometric analysis. Plast. Reconstr. Surg. 2009;124(6):2076–2084. doi: 10.1097/PRS.0b013e3181bf7e1b</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Delye H., Clijmans T., Mommaerts M.Y., Sloten J.V., Goffin J. Creating a normative database of age-specific 3D geometrical data, bone density, and bone thickness of the developing skull: a pilot study. J. Neurosurg. Pediatr. 2015;16(6):687–702. doi: 10.3171/2015.4.PEDS1493</mixed-citation><mixed-citation xml:lang="en">Delye H., Clijmans T., Mommaerts M.Y., Sloten J.V., Goffin J. Creating a normative database of age-specific 3D geometrical data, bone density, and bone thickness of the developing skull: a pilot study. J. Neurosurg. Pediatr. 2015;16(6):687–702. doi: 10.3171/2015.4.PEDS1493</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Elzaki M.M., Ayad C.E., Hassan H.A., Abdalla E.A. Anthropometric computed tomography study of certain craniofacial parameters: cephalic length and cranial width, nasal height, width and index of adult Sudanese. Glob. Adv. Res. J. Med. Med. Sci. 2015;4:467–472.</mixed-citation><mixed-citation xml:lang="en">Elzaki M.M., Ayad C.E., Hassan H.A., Abdalla E.A. Anthropometric computed tomography study of certain craniofacial parameters: cephalic length and cranial width, nasal height, width and index of adult Sudanese. Glob. Adv. Res. J. Med. Med. Sci. 2015;4:467–472.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Massimi L., Bianchi F., Frassanito P., Calandrelli R., Tamburrini G., Caldarelli M. Imaging in craniosynostosis: when and what? Childs. Nerv. Syst. 2019;35(11):2055–2069. doi: 10.1007/s00381-019-04278-x</mixed-citation><mixed-citation xml:lang="en">Massimi L., Bianchi F., Frassanito P., Calandrelli R., Tamburrini G., Caldarelli M. Imaging in craniosynostosis: when and what? Childs. Nerv. Syst. 2019;35(11):2055–2069. doi: 10.1007/s00381-019-04278-x</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hong B.Y., Ho E.S., Zellner E., Phillips J.H., Forrest C.R. Comparing cephalic index and midsagittal vector analysis in assessing morphology in sagittal synostosis: A CT-based morphometric analysis. Cleft. Palate. Craniofac. J. 2019;56(7):944–952. doi: 10.1177/1055665618815400</mixed-citation><mixed-citation xml:lang="en">Hong B.Y., Ho E.S., Zellner E., Phillips J.H., Forrest C.R. Comparing cephalic index and midsagittal vector analysis in assessing morphology in sagittal synostosis: A CT-based morphometric analysis. Cleft. Palate. Craniofac. J. 2019;56(7):944–952. doi: 10.1177/1055665618815400</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
