sibmedСибирский научный медицинский журналСибирский научный медицинский журнал2410-25122410-2520ИЦиГ СО РАН10.18699/SSMJ20230302sibmed-1103Research ArticleОБЗОРЫREVIEWSБиологическая активность и терапевтический потенциал Curcuma longa (обзор литературы)Biological activity and therapeutic potential of Curcuma longa (review)ЗапорожченкоА. А.ZaporozhchenkoA. A.

Запорожченко Александра Андреевна

630126, г. Новосибирск, ул. Вилюйская, 28

Aleksandra A. Zaporozhchenko

630126, Novosibirsk, Vilyuyskaya str., 28

alesz@yandex.ruhttps://orcid.org/0000-0001-8633-1254СуботяловМ. А.SubotyalovM. A.

Суботялов Михаил Альбертович, д.м.н.

630126, г. Новосибирск, ул. Вилюйская, 28

630090, г. Новосибирск, ул. Пирогова, 1

Mikhail A. Subotyalov, doctor of medical sciences

630126, Novosibirsk, Vilyuyskaya str., 28

630090, Novosibirsk, Pirogova str., 1

subotyalov@yandex.ruНовосибирский государственный педагогический университетРоссияNovosibirsk State Pedagogical UniversityRussian FederationНовосибирский государственный педагогический университет; Новосибирский государственный университетРоссияNovosibirsk State Pedagogical University; Novosibirsk State UniversityRussian Federation2023220620234331527Copyright © Запорожченко А.А., Суботялов М.А., 20232023Запорожченко А.А., Суботялов М.А.Zaporozhchenko A.A., Subotyalov M.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://sibmed.elpub.ru/jour/article/view/1103

В обзоре представлен анализ публикаций, посвященных выявлению биологической активности, компонентного состава, фармакологических свойств и терапевтического потенциала различных компонентов растения Curcuma longa. При подготовке настоящей публикации использовались преимущественно статьи в изданиях, включенных в PubMed, Scopus, Web of Science. Проведенный анализ показал, что Curcuma longa содержит широкий спектр биологически активных веществ, в том числе куркуминоиды, летучие масла, смолы, алкалоиды. В многочисленных исследованиях in vivo и in vitro продемонстрированы противовоспалительный, антиоксидантный, антибактериальный, противоопухолевый, нейропротекторный, антипролиферативный и ряд других эффектов. Таким образом, Curcuma longa обладает высоким терапевтическим потенциалом и может быть перспективным видом сырья для разработки средств, эффективных при различных заболеваниях.

The review presents an analysis of publications devoted to the identification of biological activity, component composition, pharmacological properties and therapeutic potential of various components of the Curcuma longa plant. This publication was prepared using mostly articles in PubMed, Scopus, and Web of Science. The analysis showed that Curcuma longa contains a wide range of biologically active substances, including curcuminoids, volatile oils, resins, alkaloids. Numerous in vivo and in vitro studies have demonstrated anti-inflammatory, antioxidant, antibacterial, antitumor, neuroprotective, antiproliferative and a number of other effects. Thus, Curcuma longa has a high therapeutic potential and can be a promising type of raw material for the development of drugs effective in various diseases.

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The authors declare that there are no conflicts of interest present.